Parham has keen interests in developing cutting-edge therapeutic technologies.
He is a former university lecturer with management experience and exceptional people skills.
Parham is also versed in laboratory tests and bioinformatics with focus on cell biology and cell-based assays. He strongly loves working on various signalling pathways.
He is a passionate researcher in cancer and desires a challenging role as a research scientist or postdoctoral fellow in cancer or immunology. His dream research is to manipulate immune cells against cancer tumours.
After a couple of years which Parham worked as a tenure-track university lecturer at Payam Noor University, he started his PhD at the University Putra Malaysia in 2013. During his PhD, Parham stablished a virtual high-throughput screening platform to find out more suitable berberine derivatives to treat breast cancer cells. His work led to ONE innovation, FIVE journal papers, ONE silver medal, and ONE governmental grant ($30000).
He is also expert in in vitro and in silico studies, and try to find new berberine derivatives against MAPK, PI3K, and Hedgehog signaling pathways.
Parham authored five high-impact journal papers based on his PhD research.
He also presented research results at international scientific meetings in the UK and Italy held by British, European, and American associations for cancer research - BACR, EACR, and AACR respectively.
Parham won Travel Award funded by UPM to attend at BPS Pharmacology, 2016, for his oral presentation. His project was funded (FRGS) by the Ministry of Higher Education in Malaysia. As long as he prepared his PhD thesis (45,000 words), he used to present annual progress report for grant awarding bodies.
For a long time, Parham was also involved in teaching and demonstrating at undergraduate practical and tutorial sessions (2000-2013) and online training workshops for many master and PhD students (2011- present).
Phytochemistry & Medicinal Chemistry (10+ years), Cell and Tissue Culture (10+ years), Protein and RNA Techniques (RT-PCR, Western blotting, DNA-based ELISA, Cell-based ELISA, Flow Cytometry, MTT assay, Enzyme targeting, Target prediction) (5+ years), Cell Signalling (5+ years), Molecular Pharmacology (5+ years)
Molecular Modelling (3 years), Computational Biology (3 years), Molecular Dynamics Simulations (2 years), Linux Shell Scripting (2 years), R Programming (New learner), Python (New learner)
Website design, SEO, Social media (10+ years), HTML coding (10+ years), MySQL (10+ years), cPANEL (10+ years), Content Management Systems (CMS) (10+ yeas), E-Commerce (10+ years), E-learning (5+ years)
Book Authoring (10+ years), Article Authoring (5+ years), Editing (5+ years), Peer-reviewing (3 years), PhotoShop and Graphics (10+ years)
Parham has taught to thousands of students who used his online professional services so far, and hundreds copies of recorded classes as DVD packages have been distributed to students national-wide. More than one hundred hours were prepared for biochemistry and cell and molecular biology in order to helping students for their postgraduate enterance Exam. They can take our online courses and exams as well.
BUT NOW, we have founded an incredible learning platform. Using this novel system, all graduates, lecturers, and educators will own their academy and at the same time they will be able to earn money from their teaching activities directly from all over the world.
January 2016 to Present
May 2017 to Present
December 2015 to Present
August 2016 to Present
Faculty of Medicine and Health Sciences
Field of Study: Pharmacology and Toxicology
MOLECULAR MODELLING OF BERBERINE DERIVATIVES AS INHIBITORS OF ONCOGENIC SIGNALLING PATHWAYS IN BREAST CANCER CELL LINES
Thesis Submitted to the School of Graduate Studies, Universiti Putra Malaysia, in Fulfillment of the Requirements for the Degree of Doctor of Philosophy in Pharmacology and Toxicology
Medical statistics (SPH5112) ; Medical genetics (HGD5502) ; Molecular pharmacology (BMS5021) ; Infection and immunity (VPM5361) ; Molecular physiology (VPM5001) ; Special topics in human genetics (HGD5509) ; Health research methods and biostatistics (PSK5000) ; Lipid in health and disease (PKK5202) ; Advanced genetics (BMS5092)
Professional knowledge of candidates in applied fields of sciences are assessed by a rigorous assessment strategy after which our new brand "iCertificate" is offered to successful candidates. We founded "ïCertificate" to qualify scientific knowledge achieved by self-study. Regarding iCertificate branding, our objective is to help talented people to have certified knowledge in special topics of interest.
Our current learning services are powerful, but we are humble and encourage lecturers and institutions to join us and use our platforms to teach and evaluate their students. We proudly launch their sites for free and will establish online teaching/assessment services for institutes, lecturers, and teachers. In addition, we freely offer unlimited space of our cloud drive for their files and videos. We care about the academia and all people involved in, and we promote institutes and graduates.
As a result of our 5 star entrepreneurial support, you will:
1) own your online teaching department.
2) own your online examination system.
3) own 1000 gigabyte of cloud space for uploading your teaching videos.
4) have your online system connected to PayPal or other payment gateways.
5) earn money from your online activities based on the number of students using your online sevices.
6) and finally of the most importance, sincerely help your students.
Postdoc fellow at Harvard Medical School, and Co-supervisor of Dr. Parham's PhD work. He is the best adviser in research methodogy and article writing.
Professor of genetics and helpful guide of Dr. Parham's PhD work
Professor of pharmacology, a knowledgeable mentor, and one examiner of Parham's PhD thesis.
Trust Parham Academy, let us help you in your future successes and ambitions.
Many pages have been written about the Coliseum and there aren’t many travelers that didn’t hear about this fabulous Roman structure that seems to have discovered the secret of eternal youth. The Coliseum in Rome is a huge amphitheater that could accommodate up to 55,000 people and was the scene of many gladiator and animal fights. Its building started in 70 AD, but the arena was inaugurated only 10 years later.
The inaugural contest was rather bloody, over 5,000 wild animals being killed during the fights and many gladiators finding their end. It seems that because of these fights several species became extinct, creatures like the Middle Easter lion and North African elephant. The Coliseum illustrates all three ancient architectural styles: Doric, Ionic and Corinthian.
The Sant Angelo Castle was actually built to be a mausoleum for Roman Emperor Hadrian. It was built sometimes between 123 and 139 AD, and looked more like a fortress than a burial place. Roman Emperor Flavius Augustus Honorius decided to incorporate the castle into Rome’s Aurelian Walls, and this process led to the disappearance of many of the mausoleum’s contents. During the medieval era it became a stronghold and eventually a prison.
Vatican City is the sovereign territory of the Holy See, ruled by the Bishop of Rome – the Pope. The Renaissance Architecture inside this walled enclave has some of the most famous cultural properties in the world.
St. Peter’s Basilica is one of the largest churches in the world. It is the burial site of its namesake Saint Peter, one of the twelve apostles of Jesus. St. Peter’s is considered one of the holiest Roman Catholic sites and is famous as a place where the Pope presides services throughout the year.
The architectural style is Late Renaissance and Baroque. The construction of the basilica took 120 years to complete (1506-1626). Numerous architects contributed to the design over the years including Donato Bramante, Antonio da Sangallo the Younger, Michelangelo, Jacopo Barozzi da Vignola, Giacomo della Porta, Carlo Maderno and Gianlorenzo Bernini.
The Vatican Museums have a large collection of works built up by the Roman Catholic Church throughout the centuries including some of the most important masterpieces of Renaissance art in the world.
Sistine Chapel is most famous for its fresco works by Michelangelo, particularly the scenes from Genesis on the ceiling, The Creation of Adam, and The Last Judgment on the altar wall.
The Leaning Tower of Pisa is actually just one of many attractions in the city of Pisa, but its fame, gained from its flaw, is world renown. Work began on the tower in the 1100s and the sinking, which led to the lean, began by the time the tower reached the third story. Prior to restoration work in the 1990s, it was predicted to topple over by the year 2000. Today, visitors can climb up the stairs of the tower for a fabulous view over the city. The Leaning Tower, also known as La Torre Pendete, stands on the Piazza del Duomo.
Venice (Italian: Venezia) is one of the most interesting and lovely places in the world. This sanctuary on a lagoon is virtually the same as it was six hundred years ago, which adds to the fascinating character. Venice has decayed since its heyday and is heavily touristed (there are 56000 residents and 20 million tourists per year), but the romantic charm remains.
The Palace of Westminster is the meeting place of the House of Commons and the House of Lords, the two houses of the Parliament of the United Kingdom. Commonly known as the Houses of Parliament after its occupants, the Palace lies on the north bank of the River Thames in the City of Westminster, in central London.
Westminster Bridge is a road-and-foot-traffic bridge over the River Thames in London, linking Westminster on the west side and Lambeth on the east side.
Red buses, black taxies, and underground railway are well-known as well as too many historical places and castles.
Big Ben is the nickname for the Great Bell of the clock at the north end of the Palace of Westminster in London.
The Victoria Tower (farther in the picture) is the square tower at the south-west end of the Palace of Westminster in London, facing south and west onto Black Rod's Garden and Old Palace Yard. At 98.5 metres (323 ft), it is slightly taller than the more famous Elizabeth Tower (formerly known as the Clock Tower and popularly known as 'Big Ben') at the north end of the Palace (96.3 metres (316 ft))
Kaboli, P.J. et al. (2016) Molecular modelling and molecular dynamics simulations of a new berberine derivative as a dual RAF inhibitor for treatment of drug resistance acquired in melanoma. Oral presentation. "Pharmacology", British Pharmacological Society, London, UK.
Kaboli, P.J. et al. (2017) Molecular modelling, molecular dynamics simulations and in vitro evaluation of Berberine as an inhibitor of MAP kinase and PI3K pathway. Poster presentation. "EACR-AACR-SIC Special Conference 2017: The Challenges of Optimising Immuno and Targeted Therapies: From Cancer Biology to the Clinic", Florence, Italy.